![]() ![]() The results demonstrated that high mRNA expressions of ANXA2, ANXA6, and ANXA7 were significantly associated with worse prognosis, while ANXA5 was correlated with better prognosis in adult AML. Quantitative reverse transcript real-time PCR (QRT-PCR) was performed to detect the ANXA2 expression level in the bone marrow-derived mononuclear cells (BMMCs) obtained from 101 pediatric AML patients and 30 controls. GenomicScape tool was used to assess the prognostic value of the expressions of Annexin family members in a cohort of 162 adult AML patients. The aim of the present study was to assess the prognostic value of Annexin expressions in adult and pediatric AML. ![]() However, the diagnosis and prognosis of Annexin family expression in acute myeloid leukemia (AML) remain elusive. Annexin family consist of 12 members, many of them are frequently dysregulated in human cancers. ![]()
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